Pantoprazole may have side effects, but it doesn’t seem to make people anxious. During clinical trials, some people who took pantoprazole said they had headaches. In clinical trials, less than 2% of people also said they had depression and dizziness (dizziness). Some clinical evidence shows that people with gastroesophageal reflux disease (GERD) can also have anxiety and depression. In one clinical study, both pantoprazole and the antidepressant amitriptyline were found to be safe and effective at treating both GERD and anxiety.
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