Deferasirox (generic name) (de FER a sir ox)
Jadenu, Jadenu Sprinkle are brand names.
Chelating agents are a drug class.
What exactly is Jadenu?
Jadenu (deferasirox) binds to iron in the bloodstream and eliminates it.
Jadenu is used in persons 2 years of age and older who have a high level of iron in their blood for an extended length of time (chronic) as a result of frequent blood transfusions.Jadenu is also used in patients over the age of 10 who have thalassemia and have an excess of iron in their blood but do not get frequent blood transfusions.
It is unknown if Jadenu is safe and effective when used with other medications to treat an excess of iron in the blood.
If you have severe kidney or liver problems, advanced cancer, a blood cell or bone marrow condition, or low platelet counts in your blood, you should not take Jadenu.
Deferasirox might be harmful to your liver and kidneys.
If you suffer swelling, shortness of breath, discomfort in your upper stomach, lack of appetite, little or no peeing, dark urine, clay-colored stools, or jaundice, contact your doctor right once (yellowing of the skin or eyes).
Jadenu may potentially cause bleeding in the stomach or intestines.
If you experience signs of stomach bleeding, such as bloody or tarry stools, or coughing up blood or vomit that looks like coffee grounds, call your doctor right once.
Prior to using this medication,
You should not use Jadenu if you are allergic to deferasirox or if you have any of the following conditions:
- illness of the liver or kidneys;
- cancer has progressed;
- a bone marrow condition; or
- platelet count is low in your blood.
To ensure that Jadenu is suitable for you, inform your doctor if you have ever had:
- kidney disorder;
- illness of the liver;
- anaemia (insufficiency of red blood cells);
- cancer (particularly blood cell cancers like leukaemia);
- an ulcer in the stomach;
- gastrointestinal or intestinal bleeding
- issues with vision or hearing; or
- a weakened immune system as a result of sickness (such as cancer, HIV, or AIDS) or treatment with steroids, chemotherapy, or radiation
It is unknown if this medication may damage an unborn child.
If you are pregnant or want to become pregnant, inform your doctor.
Jadenu may reduce the effectiveness of birth control tablets.
Consult your doctor about non-hormonal birth control (condoms, diaphragms with spermicide) to avoid pregnancy.
While taking Jadenu, you should not breast-feed.
How do I approach Jadenu?
Jadenu should be taken precisely as directed by your doctor.
Read any drug guides or instruction sheets and follow all guidelines on your prescription label.
Your doctor may order some tests to ensure that you do not have any problems that might prohibit you from taking Jadenu safely.
Every day, take Jadenu at the same time.
This medication may be taken on an empty stomach or with a modest low-fat meal.
With a full glass of water, swallow the Jadenu tablet whole.
If you are unable to swallow the pill whole, crumble it and combine it with yoghurt, applesauce, or another soft meal.
Open the package of Jadenu Sprinkles and sprinkle the medication into a spoonful of soft food.
After combining a crushed pill or sprinkles with soft food, immediately swallow the combination without chewing.
It should not be saved for subsequent use.
Blood tests may be required on a regular basis.
Your kidney or liver function may also need to be examined every 6 months, and a liver biopsy may be required.
Store at room temperature, free from heat and moisture.
What if I forget to take a dose?
Take the medication as soon as possible, but omit the missed dosage if your next dose is approaching.
Take no more than one dosage at a time.
What happens if I take too much?
Seek immediate medical treatment or dial 1-800-222-1222 for Poison Help.
What should I stay away from while taking Jadenu?
Other iron-chelating medications, such as deferoxamine (Desferal), should not be used unless prescribed by your doctor.
Avoid using aluminum-containing antacids such as Amphojel, Gaviscon, Maalox, Mi-Acid, Mylanta, Rulox, and others.
Jadenu has the potential to affect your thoughts or responses.
Be cautious if you are driving or doing anything else that needs you to be aware.
Jadenu negative effects
If you develop symptoms of an allergic response to Jadenu (hives, difficulty breathing, swelling in your face or throat) or a severe skin reaction, get immediate medical attention (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
If you get any of the following symptoms, stop taking Jadenu immediately and contact your doctor:
- difficulties with eyesight or hearing;
- Kidney disorders include infrequent or no urine, swelling in your feet or ankles, and feelings of exhaustion or shortness of breath.
- Nausea, upper stomach discomfort, itching, tiredness, lack of appetite, dark urine, clay-colored faeces, jaundice (yellowing of the skin or eyes) are all symptoms of liver disorders.
- fever, chills, mouth sores, skin sores, pale skin, easy bruising, unusual bleeding, chilly hands and feet, feeling light-headed or short of breath; or
- Bloody or tarry stools, coughing up blood, or vomit that looks like coffee grounds are all symptoms of stomach bleeding.
Serious adverse effects may be more common in elderly people.
- The following are some of the most common Jadenu side effects
- nauseousness, vomiting, and stomach discomfort
- indigestion; or
- a cutaneous rash
This is not an exhaustive list of possible adverse effects; more may arise.
For medical advice on side effects, contact your doctor.
You may contact the FDA at 1-800-FDA-1088 to report adverse effects.
Remember to keep this and all other medications out of the reach of children, never share your medications with others, and only use Jadenu for the indication indicated.
Always check with your healthcare practitioner to confirm that the information on this page pertains to your specific situation.
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