Haegarda
C1 esterase inhibitor subcutaneous (human) is the generic name (C1 ES ter ase in HIB it or)
Haegarda is a brand name.
What exactly is Haegarda?
Haegarda (complement C1 esterase inhibitor) is a man-made version of a blood protein that aids in the management of edoema in the body. This protein is deficient in those who suffer from Hereditary Angioedema (HAE). Hereditary Angioedema may induce swelling episodes as well as symptoms such as stomach troubles or difficulty breathing.
Haegarda is an injectable medication intended to reduce swelling and/or painful episodes in people with Hereditary Angioedema aged 6 and above.
Acute HAE attacks should not be treated with Haegarda. In the event of an acute HAE episode, begin personalised therapy as recommended with your health care provider.
Warnings
You should not use Haegarda if you have had life-threatening acute hypersensitivity responses (allergic reactions) to the substance, including anaphylaxis.
Prior to using this medication,
If you have ever had a life-threatening allergic response to a c1 esterase inhibitor, you should not take Haegarda.Tell your doctor if you have any of the following conditions to ensure Haegarda is safe for you:
- a stroke or clot in the blood;
- heart issues; or
- a catheter that is “in-dwelling”
inform your doctor if you are pregnant or nursing
Haegarda is derived from human plasma donations and may include viruses or other infectious organisms. Although donated plasma is screened and cleaned to lessen the danger of contamination, there is still a tiny chance that it might spread illness. Inquire with your doctor about any potential risks.
What is the best way to utilise Haegarda?
Follow your doctor’s instructions for using Haegarda precisely. Read any drug guides or instruction sheets and follow all guidelines on your prescription label. Under the skin, Haegarda is injected. Your initial dosage will be administered by a healthcare practitioner, and you may be taught how to take the drug appropriately on your own. Read and carefully read any Instructions for Use that come with your medication. Only prepare an injection when you are ready to administer it. If you don’t understand anything, go to your doctor or pharmacist. Unopened vials should be stored in the refrigerator or at a cool room temperature until the expiry date. Keep away from direct sunlight and avoid freezing. Each vial (bottle) has a single usage only. Even if there is still medication inside, throw it away after one usage. After combining Haegarda, use the injection immediately or keep it at room temperature for up to 8 hours. Haegarda does not include any preservatives. If you puncture the rubber top of a vial with a needle, you must utilise the vial immediately or discard it. Only use a needle and syringe once, then store them in a puncture-proof “sharps” container. Follow your state or local rules before disposing of this container. Keep it out of children’s and pets’ reach.
Dosing instructions.
Adult Standard Dose for Hereditary Angioedema: In HAE patients, for regular prevention against angioedema episodes. After reconstitution, Haegarda is designed for self-administration at a dosage of 60 International Units (IU) per kg body weight through subcutaneous (S.C.) injection twice weekly (every 3 or 4 days). The patient or caregiver should be taught how to deliver the subcutaneous injection.
What if I forget to take a dose?
If you miss a dosage of Haegarda, contact your doctor for instructions.To avoid angioedema, have Haegarda on hand at all times, particularly while travelling.
What happens if I take too much?
Seek immediate medical treatment or dial 1-800-222-1222 for Poison Help.
What should I avoid after the use of Haegarda?
Follow your doctor’s directions about any food, beverage, or activity limitations.
Side effects of Haegarda.
If you notice any of the following symptoms of an adverse response to Haegarda, get immediate medical attention: hives; chest tightness, rapid heartbeats, dizziness; wheezing or difficulty breathing; blue lips or gums; or swelling of your face, lips, tongue, or throat If you develop any of the following symptoms, contact your doctor right away:
- unexpected numbness or weakness on one side of the body;
- arm or leg discomfort, edoema, warmth, or redness
- severe headache, disorientation, vision, speech, or balance issues;
- soreness in the chest while taking big breaths; or
- rapid heart rate
The following are some of the most common Haegarda side effects:
- a strange or unpleasant taste in your tongue
- dizzy, headache
- nausea and vomiting
- bruising, itching, swelling, bleeding, warmth, or a hard lump where the drug was injected;
- stuffed up nose, painful throat
- hasty; or
- fever.
This is not an exhaustive list of possible adverse effects; more may arise. For medical advice on side effects, contact your doctor. You may contact the FDA at 1-800-FDA-1088 to report adverse effects.
More information
Remember to keep this and all other medications out of the reach of children, to never share your medications with others, and to only take Haegarda for the indication indicated.
Always check with your healthcare practitioner to confirm that the information on this page pertains to your specific situation.
