Generic Name: C1 esterase inhibitor subcutaneous (human) is the name of the drug’s generic form.
Drug Class: Hereditary angioedema drugs are a type of drug.
What is Haegarda?
Haegarda is made from a blood protein that helps keep the body from getting too swollen. People with a disease called Hereditary Angioedema (HAE) don’t have enough of this protein. Hereditary angioedema can lead to swelling attacks and other signs like stomach problems or trouble breathing.
Haegarda is a medicine that is injected and is used to stop swelling and/or painful attacks in people with Hereditary Angioedema who are at least 6 years old.
You shouldn’t use Haegarda to treat a sudden HAE attack. If you have a sudden attack of HAE, start the treatment that you and your doctor have talked about.
Warnings
You shouldn’t use Haegarda if you’ve had life-threatening allergic reactions (immediate hypersensitivity responses) to it, such as anaphylaxis.
Before you take this drug,
If you have ever had a dangerous allergic response to a c1 esterase inhibitor, you shouldn’t use Haegarda.
Tell your doctor if you have: a stroke or blood clot; heart problems; or a “in-dwelling” device to make sure Haegarda is safe for you.
Tell your doctor if you are pregnant or if you are nursing a baby.
Haegarda is made from human plasma that has been given, and it may contain viruses or other things that can make you sick. Plasma that has been donated is checked and treated to lower the risk of contamination, but there is still a small chance that it could spread disease. Ask your doctor if there are any risks.
Haegarda’s advice about pregnancy and breastfeeding (more)
Drugs that are similar
Berinert, Firazyr, Ruconest, Cinryze, Orladeyo, Kalbitor, stanozolol
How do I make use of Haegarda?
Use Haegarda exactly as your doctor has told you to. Follow all of the rules on the label of your prescription, and read any guides or instruction sheets that come with it.
Under the skin, Haegarda is given. Your first dose will be given by a health care worker, who may also show you how to use the medicine correctly on your own.
Instructions for Use that come with your medicine should be carefully read and followed. Don’t make a shot until it’s time to give it. If you don’t understand what to do, talk to your doctor or chemist.
Where to store unused vials: Keep in the fridge or a cool place, and use by the expiration date. Keep out of the light and don’t let it freeze.
Each bottle or capsule can only be used once. After one use, throw it away, even if there is still medicine in it.
After making Haegarda, you can use the injection right away or store it at room temperature and use it within 8 hours.
Haegarda contains no protection. Once you stick a needle through the rubber top of a bottle, you have to use it right away or throw it away.
Only use a needle and syringe once, and then put them in a “sharps” container that can’t be pierced. Follow the rules for getting rid of this container that your state or city has set. Keep it away from children and animals.
Information dosage
For adults with hereditary angioedema, the usual dose is:
Haegarda is meant to be given by self-injection twice a week (every 3 or 4 days) after it has been reconstituted. The amount is 60 International Units (IU) per kg of body weight. The patient or someone who cares for them should be taught how to give a subcutaneous shot.
Use: preventive medicine to stop Hereditary Angioedema (HAE) events from happening.
Normal dose for children with hereditary angioedema:
Haegarda is meant to be given by self-injection twice a week (every 3 or 4 days) after it has been reconstituted. The amount is 60 International Units (IU) per kg of body weight. The patient or someone who cares for them should be taught how to give a subcutaneous shot.
Use: preventive treatment to stop Hereditary Angioedema (HAE) attacks in people 6 years and older.
Information about how to take Haegarda in detail
What will happen if I don’t take a dose?
If you miss a dose of Haegarda, call your doctor to find out what to do.
Always have Haegarda on hand to stop angioedema, especially when travelling.
What happens if I overdose?
Get help from a doctor right away or call 1-800-222-1222 to reach the Poison Help line.
What should I stay away from after taking Haegarda?
Follow your doctor’s advice about what you can and cannot eat, drink, or do.
Haegarda side effects
Get medical help right away if you have hives, tightness in your chest, fast heartbeats, dizziness, wheeze or trouble breathing, blue lips or gums, or swelling of your face, lips, tongue, or throat.
Call your doctor right away if:
- Sudden numbness or weakness on one side of the body;
- Pain, swelling, warmth, or redness in an arm or leg;
- Sudden severe headache, confusion, problems with vision, speech, or balance;
- Chest pain when taking deep breaths; or
- Fast heart rate.
Common side effects of Haegarda include
- a strange or bad taste in your mouth,
- headaches, dizziness,
- nausea, vomiting,
- pain, bruising, itching, swelling, bleeding, warmth, or a hard lump where the medicine was injected,
- stuffy nose, sore throat,
- rash, or
- fever.
This isn’t a full list of all possible side effects, and there may be others. You should talk to your doctor about any side effects. You can call 1-800-FDA-1088 to tell the FDA about side affects.
What effects will other drugs have on Haegarda?
Tell your doctor about all the other drugs you are taking, especially if you are taking testosterone or birth control pills.
This list doesn’t have everything. Other drugs, such as prescription and over-the-counter medicines, vitamins, and herbal items, can interact with c1 esterase inhibitor. Not every drug combination that could happen is on this list.
Remember to keep Haegarda and all other medicines out of the reach of children, to never give your medicines to other people, and to only use Haegarda for what it was given for.
For more details,
Remember to keep Haegarda and all other medicines out of the reach of children, to never give your medicines to other people, and to only use Haegarda for what it was given for.
Talk to your doctor or other healthcare source to make sure that the information on this page applies to your situation.
Medical Disclaimer About Health Care Copyright 1996–2023 Cerner Multum, Inc. Version: 5.02.
