What exactly is Cabometyx?
Cabometyx is also used to treat liver cancer (hepatocellular carcinoma) in patients who have previously received sorafenib treatment.
Cabometyx has the potential to induce a perforation (a hole or tear) or a fistula (an irregular pathway) in your stomach or intestines.
This medication may potentially raise your chances of having major bleeding.
Prior to using this medication,
- an open skin wound (or a wound that is still healing);
- Problems with bleeding (such as bloody or tarry stools, or spitting up blood or vomit that resembles coffee grounds);
- elevated blood pressure;
- liver illness or
- a pre-existing dental issue
Cabometyx should be taken as directed.
Cabometyx should be taken on an empty stomach, at least 1 hour before or 2 hours after eating anything.
Cabometyx should not be taken with food.
Adult Standard Dose for Renal Cell Carcinoma:
Tablets: -As a single agent: 60 mg orally once a day until clinical benefit is lost or unacceptable toxicity occurs.-When used in conjunction with nivolumab, 40 mg once daily until disease progression or intolerable toxicity.
When using this medication in conjunction with nivolumab, consult the nivolumab prescribing information.-In combination with nivolumab, authorised for the first-line treatment of patients with advanced renal cell carcinoma (RCC).
Adult Standard Dose for Hepatocellular Carcinoma:
Tablets: 60 mg orally once daily until clinical benefit is no longer obtained or unacceptable toxicity develops.
For patients with hepatocellular carcinoma (HCC) who have previously received sorafenib treatment.
What if I forget to take a dose?
What happens if I take too much?
What should I stay away from while taking Cabometyx?
Cabometyx Adverse Effects
If you develop any of the following symptoms, contact your doctor right away:
- severe headache, impaired vision, and pounding in the neck or ears;
- Severe and continuous vomiting, diarrhoea, or constipation;
- jaundice (skin or eye yellowing);
- swollen hands, arms, legs, or feet;
- easy bruising or bleeding (nosebleeds, bleeding gums, excessive monthly flow, or persistent bleeding);
- If you experience specific side effects, your cabozantinib dosages may be delayed or withdrawn permanently.
- crimson or tarry stools, coughing up bloody mucous, or vomiting that resembles coffee grounds;
- pain, blisters, bleeding, or a severe rash in the palms of your hands or soles of your feet.
- Confusion, difficulty thinking, weakness, alterations in vision, seizure;
- a sense of dizziness, as if you’re about to pass out;
- numbness or pain in the jaw, red or swollen gums, loose teeth, or poor healing following dental work
- Fever, mouth sores, skin sores, sore throat, cough, and difficulty breathing due to low white blood cell numbers.
- Adrenal gland issues include nausea, vomiting, excessive weariness, dizziness, weakness, and fainting.
- Sudden numbness or weakness on one side of your body, problems with vision or balance, difficulty speaking or comprehending what is said to you, chest pain, difficulty breathing, swelling or pain in an arm or leg are all symptoms of a stroke or blood clot.
- Cabometyx may cause the following adverse effects:
- stomach cramps, nausea, vomiting, loss of appetite, diarrhoea, and constipation.
- In your mouth or throat, you may have pain, redness, swelling, or sores.
- Changes in taste, difficulty speaking;
- Cold symptoms include a stuffy nose, sneezing, a sore throat, and a cough.
- rash, aches and pains in your muscles, bones, and joints
- abnormal liver function tests or other types of blood testing.
- being fatigued;
- loss of weight; or
- The colour of my hair is lightening.