Abilify Asimtufii

How to say it: a-BIL-i-fy AH-SIM-TUH-FYE
Generic name: Aripiprazole is its generic name
Dosage form: extended-release injectable suspension for intramuscular administration

What does Abilify Asimtufii mean?

Atypical antipsychotics like Abilify Asimtufii are used to treat schizophrenia and bipolar I disorder in adults. The drug is given as an extended-release shot every two months.

Abilify Asimtufii is thought to work by keeping the amounts of serotonin and dopamine in the brain in check. However, the exact way it works to treat schizophrenia and bipolar I disorder is not known.

Abilify (aripiprazole) comes in different forms, such as oral pills, an extended-release injection given once a month, and a tablet called Abilify MyCite that has an ingestible sensor built into it.

Abilify Asimtufii is a slow-release injection that works longer and is given every two months. This makes it easier for patients to stick to their treatment plan and means they only need six doses a year.

How is Abilify Asimtufii used to help something?

The FDA has cleared Abilify Asimtufii as a medicine for adults with schizophrenia. It is also used alone (monotherapy) to treat adults with bipolar I disorder and keep their condition under control.

Schizophrenia is a mental illness that causes problems with how people think, what they see, how they feel, and how they connect with others.

If someone has bipolar I disorder, their mood, energy, activity level, and ability to focus can change in strange ways.

People who have schizophrenia or bipolar I disease need to be treated for a long time.

Be careful/Warnings

Abilify Asimtufii is not approved for use in older people who are psychotic because of dementia.

Suicidal thoughts can happen to people who are depressed or have a mental illness. Some teens may have more suicide thoughts when they first start taking medicine for depression. Tell your doctor right away if your mood or behavior changes quickly or if you think about committing suicide.

If you stop taking aripiprazole all of a sudden, you might experience unpleasant withdrawal effects.
Before you know how aripiprazole affects you, don’t drive or do other things that need you to be alert or have good eyesight.

People who take drugs like this have gained weight, had high blood sugar or diabetes, and had high cholesterol. These may make it more likely that you will get heart or brain blood vessel problems.

Drugs like this one have been known to cause low white blood cell numbers. This could make you more likely to get an infection. Infections have only rarely killed people. If you’ve ever had a low white blood cell count, you should tell your doctor. If you have fever, chills, or a sore throat, you should call your doctor right away.

Before you take this medicine

This medicine shouldn’t be taken by people who are allergic to aripiprazole or any of the other ingredients that don’t do anything.

This medicine is not meant to be used in older people with dementia-related psychosis because it may raise their risk of death.

Tell your doctor if you have had a heart attack or heart problem;

  • if you have high or low blood pressure;
  • if you or someone in your family has diabetes;
  • if you have seizures; or
  • if your white blood cell (WBC) count is low.
  • This will help make sure that Abilify Asimtufii is safe for you.

Suicidal thoughts can happen to people who are depressed or have a mental illness. Some teens may have more suicide thoughts when they first start taking medicine for depression. Watch out for changes in your symptoms or mood. People who care for you should also keep an eye out for rapid changes in how you act.

If you take this medicine, your blood sugar level could rise too high. If you have diabetes, keep a close eye on your blood sugar.

Pregnancy/Giving birth

If you are pregnant or want to become pregnant, you should let your doctor know. This medicine could be bad for your future child. If you take this medicine during your third trimester of pregnancy, it’s possible that your baby will have withdrawal symptoms or muscles that move in strange ways after birth.

Talk to your doctor about the risks this medicine may pose to your future child if you take it while you are pregnant. Don’t stop taking the medicine without first talking to your doctor.

If you get pregnant or think you might be pregnant while you are being treated, you should tell your doctor right away. If you get pregnant while you are being treated, you should talk to your doctor about joining the National Pregnancy Registry for Atypical Antipsychotics. Call 1-866-961-2388 or go to http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/ to sign up.

Having a baby: Breastfeeding

If you are breastfeeding or plan to nurse, let your doctor know. It’s not known if this medicine will hurt your baby if it gets into your breast milk. You should talk to your doctor or nurse about the best way to feed your baby while they are treating you.

How do you give Abilify Asimtufii?

For people who have never taken aripiprazole, you should first see how well they tolerate oral aripiprazole before starting treatment with this shot. Because oral aripiprazole has a half-life, it could take up to two weeks to fully test how well it works.

Your doctor must give you a shot of Abilify Asimtufi into the muscles in your buttocks. Do not use any other method to give the medicine.

Allow Asimtufii to be given once every two months.

People who are taking oral antipsychotics

If a person is already taking oral aripiprazole and wants to start getting the Abilify Asimtufii shot, they should get the first dose of it along with 10 mg to 20 mg of oral aripiprazole every day for 14 days.

For people who are already steady on another oral antipsychotic and know they can handle aripiprazole, the first Abilify Asimtufii injection should be given for 14 days straight along with the oral antipsychotic.

People who are taking Abilify Maintena

For people who are taking Abilify Maintena (once a month dose), give them Abilify Asimtufii 960 mg (once every two months dose) instead of their next Abilify Maintena shot. It is possible to give the first shot of Abilify Asimtufii instead of the second or later injection of Abilify Maintena.

There may be a drop in the dose to 720 mg every two months if the 960 mg dose causes bad effects.
The Abilify Asimtufii shot can be given up to two weeks before or after the end of the two-month period.

Information on dosage

Normal Adult Dose of Abilify Asimtufii for Schizophrenia

Dose: 960 mg given as a single shot every two months.

It is used to treat schizophrenia in people.

  • If a patient has bad effects, the dose can be lowered to 720 mg.
  • For people who have never taken aripiprazole before, make sure they can handle oral aripiprazole before starting treatment.

A healthcare worker should give it by intramuscular injection in the gluteal muscle. It should not be given any other way.

The usual dose of Abilify Asimtufii for adults with bipolar I disorder

Dose: 960 mg given as a single shot every two months.

Maintenance medication is used to treat bipolar I disorder in adults.

  • If a patient has bad effects, the dose can be lowered to 720 mg.
  • For people who have never taken aripiprazole before, make sure they can handle oral aripiprazole before starting treatment.
  • Give by a healthcare professional giving an intramuscular shot in the gluteal muscle. Do not use any other method to give the medicine.

How do I know if I missed a dose?

The next dose should be given as soon as possible if it has been more than 8 weeks but less than 14 weeks since the last one. The plan of every two months should be put back in place.

If it’s been more than 14 weeks since the last injection, you should start taking aripiprazole by mouth again for 14 days before the next injection.

What should I stay away from while taking this medicine?

If you get up too quickly from sitting or lying down, you might get dizzy. Do not drive or do anything else that could be dangerous until you know how aripiprazole will make you feel. Feeling sleepy or dizzy can lead to crashes, falls, or serious injuries.

Before you know how this injection makes you feel, don’t drive a car, work with machinery, or do anything else that could be risky. This medicine could change the way you think, feel, or move.

Avoid drinking alcohol. Side effects that are dangerous could happen.

You might be more sensitive to very hot weather while taking aripiprazole. Do not get too hot or too thirsty. Especially when it’s hot outside or when you’re working out, drink a lot of water.

Side affects of Abilify Asimtufi

If you think you might be having an allergic response to aripiprazole, call 911 right away: face, lips, tongue, or throat swelling; hives; trouble breathing; allergic reactions.

If your mood or behavior changes quickly or in new ways, like if your depression or anxiety gets worse, if you have panic attacks, if you have trouble sleeping, or if you feel hostile, angry, restless, more active or talkative, or if you have thoughts about killing yourself or hurting yourself, you should tell your doctor right away.

When you have severe agitation, distress, or restlessness, twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs, a mask-like appearance on your face, trouble swallowing, or speech problems, you should call your doctor right away. If you are having a seizure, your muscles will be very stiff, you will sweat a lot, and you will feel like you might pass out. If your blood cell count is low, you should also call your doctor right away.

While taking this medicine, you might feel stronger urges to be sexual, bet, or do other strong things. In this case, you should talk to your doctor.

  • blurred vision;
  • more saliva or drooling;
  • stiff muscles;
  • uncontrolled muscle movements, shaking, anxiety, or feeling restless;
  • weight gain;
  • nausea, vomiting, or constipation;
  • an increase or decrease in appetite;
  • headaches, dizziness, drowsiness, or feeling tired;
  • trouble sleeping (insomnia); or
  • cold symptoms like a stuffy nose, sneezing, or a sore throat.

This isn’t a full list of side effects; you may experience more. If you are worried about side effects, call your doctor. Call 1-800-FDA-1088 to tell the FDA about side effects.

What other drugs will have an effect on Asimtufii?

As well as prescription and over-the-counter drugs, vitamins, and herbal products, you should tell your doctor about all of the medicines you take.

Abilify Asimtufii and other drugs may have dangerous side effects when taken together. Other medicines might not work as well after getting this shot, and vice versa.

The person who treats you can let you know if it is okay to get this shot along with your other medicines. Do not start or stop taking any medicines during your treatment without first talking to your doctor or nurse.

Know what drugs you take. Make a list of them to show your doctor and pharmacist the next time you get a new drug.

If you take any of the following drugs, you should tell your doctor right away:

Biaxin, fluoxetine, paroxetine, and nefazodone are antidepressants. Fluconazole, ketoconazole, and itraconazole are antifungals. Quinidine is a medicine used to treat anxiety.

Drugs for HIV, like indinavir (Crixivan), ritonavir (Norvir), saquinavir (Fortova, Invirase), and lopinavir/ritonavir (Kaletra)

The drugs are carbamazepine (Tegretol) and rifampin (Rifadin).

To see if you have already talked to Abilify Asimtufii, click on the link below.

Storage

Keep it at 25°C (77°F), but it can go from 15°C to 30°C (59°F to 86°F).

Things used: Ingredients

Aripiprazole monohydrate is the active ingredient.

Carboxymethylcellulose sodium, polyethylene glycol 400, povidone, sodium chloride, sodium phosphate monobasic monohydrate, sodium hydroxide, and water for injection are all ingredients that don’t do anything.

The Company

It is sold and distributed by Otsuka America Pharmaceutical, Inc. in Rockville, MD 20850.
Lundbeck, Deerfield, IL 60015 USA, is in charge of marketing.

For more information

Always check with your healthcare provider to make sure that the information on this page is correct for you.

Medical Disclaimer

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About the Author: Daniel